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. 2016 Jul-Aug;48(4):424–429. doi: 10.4103/0253-7613.186189

Figure 2.

Figure 2

Effects of L-NAME, ARL-17477, 1400 W and L-NIO on mean pressure of spontaneous contractions of colonic tissues isolated from control and IBS-rats. The mean pressure value of L-NAME was higher in both control and IBS groups at concentration of 10-4 mol/L. (a) P < 0.05 vs own base values assessed by Friedman test followed by Wilcoxon signed rank tests. The mean pressure value of ARL-17477 was higher in the only control group at concentrations of 10-7 and 10-6 mol/L, but was not in IBS group. (b) P < 0.05 vs own base value assessed by Friedman test followed by Wilcoxon signed rank tests. 1400 W (10-6, 10-5 mol/L) and L-NIO (10-6, 10-5 mol/L) had no significant effect on spontaneous colonic activity in both control and IBS groups (P > 0.05)