TABLE I. Characteristics of 31 patients with cutaneous leishmaniasis treated with intralesional meglumine antimoniate, Centro de Pesquisas René Rachou - Fundação Oswaldo Cruz (Fiocruz), Belo Horizonte, Minas Gerais, Brazil, 2016.
Characteristic | Median (IR) |
---|---|
Age (years) | 63 (41-76) |
Lesion length before treatment (IR, weeks) | 16 (8-28) |
Lesion size (cm2) | 1.7 (0.8-6.6) |
Gender | n (%) |
Male | 15 (48) |
Female | 16 (52) |
Disease type | n (%) |
Primary cutaneous leishmaniasis | 27 (87) |
Relapsed cutaneous leishmaniasis | 4 (13) |
Number of lesions per patient | n (%) |
one | 22 (70.9) |
two | 6 (19.4) |
three | 3 (9.7) |
Lesion location | n (%) |
Head/neck | 10 (32.3) |
Arms/hand | 10 (32.3) |
Leg | 7 (22.6) |
Chest/back | 4 (12.9) |
Lesion type | n (%) |
Ulcer | 17 (54.8.0) |
Papule | 8 (25.8) |
Plate | 6 (19.4) |
Intralesional therapy indication | n (%) |
Systemic antimony contra-indication | 18 (58.1) |
Previous systemic antimony treatment failure | 5 (16.1) |
Serious adverse event with systemic antimony | 4 (12.9) |
Social or logistic reasons | 4 (12.9) |
Systemic antimony contra-indications* | n (%) |
Elderly | 13 (41.9) |
Heart disease | 10 (32.2) |
Renal disease | 6 (19.4) |
Alcohol abuse | 2 (6.5) |
Enlarged QTc interval | 2 (6.5) |
Continuous use of medications that extend QTc interval | 1 (3.2) |
Liver disease | 1 (3.2) |
IR: interquartile range (25-75%); *: some patients presented more than one contraindication condition.