TABLE 1.
Species | Amino acid - position 170* | CWD – IC† | CWD – PO | References |
---|---|---|---|---|
Elk | N | ND | +++ | 54, 55 |
Fallow deer | N | +++ | ND | 56 |
Mule deer | N | ND | +++ | 57 |
White-tailed deer | N | +++ | +++ | 7, 58 |
Reindeer | N | ND | ++ | 59 |
Reeves' muntjac deer | N | ND | +++ | 60 |
Red deer | N | ND | +++ | 61 |
Shira's moose | N | ND | +++ | 62 |
Squirrel monkey | S | +++ | +++ | 22-24 |
Macaque | S | 0 | 0 | 23,24 |
Tg(humanPrP) (129V) | S | 0 | ND | 38,39 |
Tg(humanPrP) (129M) | S | 0 | ND | 17,36,38,39 |
Tg(humanPrP) (129MV) | S | 0 | ND | 39 |
Sheep | S | +‡ | ND | 27 |
Tg(ovine PrP) | S | 0 | ND | 36 |
Cattle | S | ++ | 0 | 26 |
Tg(bovine PrP) | S | 0 | ND | 36 |
Raccoon | S | 0 | ND | 34 |
Ferret | S | +++ | 0 | 31,32 |
Mink | S | ++ | 0 | 35 |
Cat | S | ++ | 0 | 63 |
Chinese hamster | N | ++ | ND | 33 |
Armenian hamster | N | + | ND | 33 |
Syrian golden hamster | N | + | ND | 33 |
Djungarian hamster | N | 0 | ND | 33 |
Siberian hamster | N | + | ND | 33 |
Tg(hamsterPrP) | N | ++ | ND | 33 |
Prairie vole | N | +++ | ND | 30 |
Meadow vole | N | +++ | ND | 29 |
Red-backed vole | S/N | +++ | ND | 29 |
Bank vole | N | +++ | ND | 19 |
Deer mouse | N | ++ | ND | 29 |
White-footed mouse | N | ++ | ND | 29 |
C57/BL6 mouse | S | 0 | ND | 33 |
Tg(mousePrP)-overexpressing PrP | S | +, +++ | ND | 36,64 |
Human numbering.
+++: 75–100%, ++: 25–74%, +: 0–24% to terminal prion disease.
ARQ/VRQ only.