TABLE 1.
Functional summary of Hsp31 and paralogs.
| Function/Attribute | Hsp31 | Hsp32 | Hsp33 | Hsp34 |
|---|---|---|---|---|
| Catalytic triad | Yes | Yes | Yes | Yes |
| Chromosome Position | Interstitial | Telomeric | Telomeric | Telomeric |
| Sequence homology | ˜70% | >90% | >90% | >90% |
| Chaperone activity | +++ | +++ | +++ | +++ |
| Methylglyoxalase | +++ | +/− | +/− | +/− |
| Deglycase | +++ | ND | ND | ND |
| Role in Autophagy | + | + | + | + |
| Peak mRNA level | Early SP | DS | Early SP | ND |
| Peak steady state protein level | SP | ND | ND | ND |
| Stress granule and P body localization | Yes | Yes | ND | ND |
| Mitochondrial localization | Yes | ND | ND | ND |
ND = Not determined
SP = Stationary Phase
DS = Diauxic shift