Table 1. Direct regulators of egl-1 BH3-only transcription.
Transcriptional regulators | Cells | Function in egl-1 transcription | Reference |
---|---|---|---|
TRA-1 | HSN | repressor | Conradt and Horvitz 1999 |
HLH-2, HLH-3 | NSM sister | activator | Thellmann et al. 2003 |
CES-1 | NSMa | repressor | Thellmann et al. 2003 |
CEH-20, MAB-5 | P11.aaap | activator | Liu et al. 2006 |
CEH-20, LIN-39, UNC-62 | VC neurons | repressor | Potts et al. 2009 |
CEH-34, EYA-1 | M4 sister cell | activator | Hirose et al. 2010 |
EFL-3, LIN-39 | VA and VB neurons | repressor | Winn et al. 2011 |
SPTF-3 | M4 sister cella | activator | Hirose and Horvitz 2013 |
LIN-1 | g1A sister, I1 sistera | activator | Jiang and Wu 2014 |
UNC-3 | RID sister | activator | Wang et al. 2015 |
Direct regulators of egl-1 transcription identified that either function as repressors or activators of egl-1 transcription in specific cells.
Indicates that this particular transcriptional regulator affects the programmed death of additional cells.