Table 2.

Single locus analysis results for regions genotyped in the replication study.

Marker	Region Name	Maj/MinA	MAFB Case / CtrlC	PGWAS	Model	OR (95% CID)	P Meta RepE	Q / I2 Meta RepE	OR (95% CID) Meta RepE	P Meta OverallF	Q / I2 Meta OverallF	OR (95%CID) Meta Overall
rs2267828	GTF2IRD1	A/G	0.40 / 0.45	7.02×10−7	Add	0.79 (0.72-0.87)	0.02	0.56 / 0	0.87 (0.77-0.98)	6.46×10−8	0.41 / 0	0.81 (0.76-0.88)
rs10901656	DOCK1	C/T	0.27 / 0.23	6.91×10−7	Dom	1.39 (1.22-1.58)	0.095	0.6 / 0	1.14 (0.98-1.31)	9.56×10−6	0.23 / 28.72	1.21 (1.12-1.32)
rs11235667	FCHSD2-P2RY2	A/G	0.07 / 0.11	1.03×10−8	Add	0.59 (0.50-0.71)	0.0014	0.29 / 18.43	0.71 (0.57-0.87)	6.67×10−11	0.14 / 44.37	0.63 (0.55-0.72)
rs1048257	AHNAK2	T/C	0.34 / 0.39	1.67×10−6	Add	0.79 (0.72-0.87)	0.086	0.29 / 17.06	0.90 (0.80-1.01)	8.66×10−7	0.12 / 47.82	0.82 (0.76-0.89)

^AMaj/Min = Major/Minor allele

^BMAF = Minor allele frequency

^CCase/Ctrl = Case/Control

^DCI = Confidence interval

^EMeta Rep = Meta-analysis for the replication