Fig 6. KRT17, pAKT1, MTOR, phosphorylated EIF4EBP1 (pEIF4EBP1) and SLC2A1 were concurrently upregulated in oral squamous cell carcinoma (OSCC).

(A) Representative images of immunohistochemical expression of KRT17, MTOR, pEIF4EBP1, SLC2A1 and pAKT1 in normal oral epithelium (normal) and OSCC (cancer). HE, hematoxylin and eosin staining. Scale bar, 100 μm. (B) Schematic representation of the immunohistochemical expression of KRT17, MTOR, pEIF4EBP1, SLC2A1 and pAKT1 in 50 OSCC cases. A blue square denotes increased expression in the individual OSCC case compared with the normal epithelium as an internal control. A white square denotes no immunohistochemical expression. A light-blue square denotes weak staining comparable to that in the normal epithelium. There was not a single case of downregulation of these proteins in OSCC.