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. 2016 Aug 11;11(8):e0160993. doi: 10.1371/journal.pone.0160993

Fig 3. Linagliptin reduces type I and III collagen expression in mice with peritoneal fibrosis.

Fig 3

Immunohistochemical analyses of (a) type I collagen and (b) type III collagen expression in peritoneal tissues on day 21 (original magnification: ×200) in control mice, MGO-injected mice treated with saline, and MGO-injected mice treated with linagliptin. The numbers of type I and III collagen pixels were increased on day 21 in MGO-injected mice treated with saline but significantly decreased in MGO-injected mice treated with linagliptin (c, d). Statistical analyses were performed using ANOVA followed by Tukey’s post-hoc test. *P < 0.05.