Table 3. correlation between white-matter microstructure and Emotion Attribution scores in ALS patients.
clusters | localization | x,y,z | Cluster size | Partial correlation | p-value |
---|---|---|---|---|---|
#1 | forceps minor | -18, 31, 19 | 1689 | 0.76 | 0.0002 |
#2 | uncinate fasciculus, inferior fronto-occipital fasciculus- | 15, 35, -11 | 570 | 0.79 | 0.000034 |
#3 | superior longitudinal fasciculus | -32, 12, 24 | 77 | 0.65 | 0.006 |
#4 | genu of corpus callosum, forceps minor | -5, 24 15 | 53 | 0.81 | 0.000011 |
The table shows localization, MNI coordinates (x,y,z) and size (number of voxels) of significant fractional anisotropy (FA) clusters emerged form the TBSS correlation analysis in ALS patients. Coefficients and p-values relative to the partial correlation analysis between EA scores and mean FA values extracted from significant clusters with disease duration (i.e., months from symptoms onset) as controlling variable are also reported. P-values were adjusted for multiple comparisons with the False Discovery Rate correction.