Table 1.

Participant demographic and clinical characteristics at baseline

Categorical Variables
	Community Care (N = 181)		NAVIGATE (N = 223)
	N	%	N	%	Unadjusted p-value1	F test statistic2	Degrees of freedom2	p-value2
Male	120	66	173	78	0.04	3.86	1, 370	0.05†
Race					0.01	1.28	2, 336	0.28
White	80	44	138	62
African American	89	49	63	28
Other	12	7	22	10
Hispanic ethnicity	18	10	55	25	0.01	3.24	1, 370	0.07
Marital status					0.67	0.28	2, 336	0.76
Presently married	10	6	14	6
Widowed/divorced/separated	8	4	14	6
Never married	163	90	195	87
Current residence					0.97	0.08	3, 302	0.97
Independent living	32	18	40	18
Supported or structured	7	4	7	3
Family, parents, grandparents, sibling	129	71	158	71
Homeless, shelter, or other	13	7	18	8
Patient's education					0.74	0.36	3, 301	0.78
Some college or higher	54	30	71	32
Completed high school	58	32	75	34
Some high school	58	32	67	30
Some or completed grade school	11	6	9	4
Mother's education					0.17	1.06	3, 302	0.37
Some college or higher	65	36	102	46
Completed high school	51	28	60	27
Some high school or grade school	32	18	27	12
No school or unknown	33	18	34	15
Current student	47	26	35	16	0.01	4.77	1, 370	0.03†
Currently working	30	17	28	13	0.25	1.30	1, 370	0.25
Type of insurance					0.03	1.28	2, 333	0.28
Private	27	15	55	25
Public	66	37	61	27
Uninsured	88	49	104	47
SCID diagnoses					0.60	0.58	5, 234	0.72
Schizophrenia	101	56	113	51
Schizoaffective bipolar	13	7	11	5
Schizoaffective depressive	25	14	32	14
Schizophreniform provisional or definite	24	13	43	19
Brief psychotic disorder	1	1	1	1
Psychotic disorder not otherwise specified	17	9	23	10
Lifetime alcohol use					0.08	2.49	2, 336	0.08
Did not meet criteria	123	68	134	60
Met abuse criteria	16	9	36	16
Met dependence criteria	42	23	53	24
Lifetime cannabis use					0.22	146	2, 336	0.23
Did not meet criteria	123	68	137	61
Met abuse criteria	21	12	39	18
Met dependence criteria	37	20	47	21
Prescribed one or more antipsychotics at consent	155	86	182	82	0.28	0.36	1, 370	0.55
Number of prior hospitalizations					0.01	3.91	1, 368	0.05†
0	34	19	54	24
1	75	41	106	48
2	32	18	37	17
3 or more	40	22	24	11
Continuous Variables
	Community Care (N = 181)		NAVIGATE (N = 223)
	Mean	standard deviation	Mean	standard deviation	Unadjusted p-value	F test statistic	df	p-value*
Age	23.08	4.90	23.18	5.21	0.83	0.14	1, 370	0.71
Duration of untreated psychosis (weeks)	211.43	277.49	178.91	248.73	0.35^	0.97	1, 369	0.33
Heinrichs-Carpenter Quality of Life Scale
Total score	54.77	18.99	50.89	18.44	0.04	2.70	1, 369	0.10
Interpersonal relations	20.07	8.53	19.51	8.84	0.52	0.51	1, 369	0.48
Instrumental role	6.82	6.86	4.54	6.07	0.01	7.51	1, 369	0.01
Intrapsychic foundations	21.39	7.29	20.36	6.69	0.14	1.60	1, 369	0.21
Common objects and activities	6.49	2.25	6.48	2.36	0.95	0.03	1, 369	0.86
Positive and Negative Syndrome Scale
Total score	74.54	14.87	78.32	14.95	0.01	5.56	1, 369	0.02†
Factor Scores (30)
Positive	12.13	3.79	12.32	3.88	0.62	0.32	1, 369	0.57
Negative	16.34	4.96	16.98	5.34	0.22	0.80	1, 369	0.37
Disorganized/concrete	7.34	2.63	8.18	2.83	0.01	7.03	1, 369	0.01
Excited	6.38	2.30	7.05	3.06	0.02	5.83	1, 369	0.02
Depressed	7.93	3.42	8.16	3.22	0.49	0.34	1, 369	0.56
Calgary Depression Scale for Schizophrenia	4.66	4.30	4.65	4.27	0.99	0.01	1, 369	0.99
Clinical Global Impressions Severity Scale	3.96	0.83	4.12	0.80	0.05	3.37	1, 369	0.07
Duration of lifetime anti-psychotic medication at consent (days)	48.46	48.98	40.60	42.88	0.13^	2.74	1, 369	0.10

¹not adjusting for cluster randomized design

²adjusting for cluster randomized design

SCID = Structured Clinical Interview for DSM-IV.

^*p-values are based on a linear, negative binomial, logit or generalized logit mixed effects model to account for cluster-randomized design.

The variables marked † were included as covariates in the adjusted model in following analyses.

^{^}For the duration measures, the unadjusted p-values are of the Mann-Whitney U test.