Table 1.
The distribution of demographic factors, reproductive and medical history, by PCOS history among all subjects (cases (n=1508) and controls (n = 1556)), LIBCSP 1996–1997.
| Factor | PCOS (n=67) | No PCOS (n=2,997) | Total (n=3,064) |
|---|---|---|---|
| Age | 53.8±12.2 | 58.0±12.8 | 57.8±12.8 |
| BMI (kg/m2) | 27.4±6.2 | 26.5±5.7 | 26.5±5.7 |
| BMI at age 20 (kg/m2) | 21.4±3.9 | 20.9±3.1 | 20.9±3.2 |
| Parity (%) | |||
| 0 | 10 (14.9) | 359 (12.0) | 369 (12.0) |
| 1 | 7 (10.5) | 307 (10.5) | 314 (10.5) |
| ≥2 | 50 (74.6) | 2,331 (77.5) | 2,381 (77.4) |
| Race (%) | |||
| White | 63 (94.0) | 2,777 (92.8) | 2,840 (92.8) |
| Black and other | <5 | 217 (7.2) | 221 (7.2) |
| Age at menarche (years) | 12.4±7.5 | 12.6±1.6 | 12.6±1.6 |
| Age at first birth (years) | 25.1±3.8 | 25.3±4.6 | 25.3±4.6 |
| No. of postmenopausal women (%) | 35 (55.6) | 1,961 (67.4) | 1,996 (65.1) |
| Physical activity (hours/week) | 6.4±10.2 | 7.3±10.0 | 7.3±10.0 |
| Ever use of oral contraceptives (%) | 37 (55.2) | 1335 (44.6) | 1,372 (44.8) |
| Family history of breast cancer (%) | 12 (18.5) | 480 (16.5) | 492 (16.6) |
| Periods never became regular naturally (%) | 16 (24.2) | 299 (10.3) | 315 (10.6) |
| History of infertility due to ovulatory dysfunction (%) | 6 (12.0) | 44 (1.7) | 50 (1.9) |
| Metabolic syndrome-related sequelae (%) | |||
| Hypertension | 21 (33.3) | 999 (34.4) | 1,020 (34.4) |
| Diabetes mellitus | <5 | 236 (8.1) | 239 (8.0) |
| Hypercholesterolemia | 22 (34.9) | 888 (30.5) | 910 (30.6) |
| History of active smoking (%) | 37 (57.8) | 1,616 (55.3) | 1,653 (55.4) |