Table 3.
Immunohistochemical profiles of biphenotypic sinonasal sarcoma and its histologic mimickers.
| S10 0 |
Acti n |
β- catenin (nuclea r) |
SOX1 0 |
Fact or XIIIa |
Cytokera tin |
Desm in |
Myogen in |
|
|---|---|---|---|---|---|---|---|---|
|
Biphenotypic sinonasal sarcoma |
+ or F+ |
+ or F+ |
+ or F+ | − | F+ | −/F+ | −/F+ | −/F+ |
|
Malignant Peripheral Nerve Sheath Tumor |
F+ | − /F+ |
− | F+/− | −/F+ | −/F+ | −/F+ | |
|
Cellular schwannoma |
+ | − | − | + | − | − | − | − |
| Leiomyosarcoma | − | + | − | − | −/+ | + | − | |
| Fibrosarcoma | − | − | − | − | − | − | − | |
| Glomangiopericytoma | − | + | + | − | + | − | − | − |
| Synovial Sarcoma | −/+ | −/+ | +/− | − | F+ | −/F+ | −/F+ |
+: consistently positive; − : consistently negative; F+: focally positive (<10% of cells); −/F+: usually negative, but sometimes focally positive; F+/−: usually focally positive, but sometimes negative; blank: unknown due to limited data.