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. Author manuscript; available in PMC: 2016 Aug 31.
Published in final edited form as: Cell Rep. 2016 Jul 28;16(6):1653–1663. doi: 10.1016/j.celrep.2016.06.101

Figure 4. Deletion of miR-17-92 in adult hippocampal neural progenitors alters expression levels of genes in the glucocorticoid pathway.

Figure 4

(A) Schematic flow of gene expression analysis. The adult hippocampal samples from 12 weeks old wild type (WT) and miR-17-92 knockout (KO) mice were analyzed by RNA-Sequencing to detect genes with altered expression.

(B) Gene ontology (GO) analysis of 150 predicted target genes indicated 10 most significantly overrepresented functions. The glucocorticoid-mediated signaling pathway was the top among altered functions.

(C) Gene ontology analysis of signaling pathways that are associated with the Sgk1 function. See details in Experimental Procedures. See also Figure S4.