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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Hum Pathol. 2016 May 14;55:117–125. doi: 10.1016/j.humpath.2016.04.017

Figure 2.

Figure 2

A: Representative HGPIN lesion (P) from radical cystoprostatectomy with adjacent benign glandular epithelium (B) (200× magnification). B: prominent nucleoli are apparent in HGPIN cells (P) compared to adjacent benign luminal cells (B) (630× magnification). C: Immunostaining with PIN4 cocktail for high molecular weight keratin and p63 demonstrates positively staining basal cells (brown) in both benign (B) and HGPIN (P) glands (200× magnification). Racemase positivity (red) is seen in HGPIN lesion. D: ERG is expressed in nuclei of HGPIN (P) lesion but is negative in adjacent benign (B) glands (200× magnification).