Table 1.

List of microRNAs altering disease physiology by targeting raft proteins (caveolin and flotillin)

miRNA	Target	Activity	References
miR‐133a	Caveolin‐1	Regulates migration and invasion in head and neck squamous cell carcinoma	32
miR‐124	Caveolin‐1	Reduces caveolar density in porcine kidney cells and regulates caveolae‐mediated endocytosis of pathogens	41
	Flotillin‐1	Regulates migration and invasion in breast cancer cells	38
	Flotillin‐2	Regulates mouse acrosome biogenesis during spermatogenesis	40
miR‐203	Caveolin‐1	Regulates migration and invasion in pancreatic cancer cells	33
		Regulates longevity and aging in breast tissue during caloric restriction	37
miR‐138	Flotillin‐1, ‐2, Caveolin‐1	Regulates nuclear factor‐κB signalling pathway involved in aggressiveness of oesophageal squamous cell carcinoma	39
miR‐103/107	Caveolin‐1	Regulates insulin sensitivity in obese mice	42
miR‐199‐5p	Caveolin‐1	Regulator of tissue fibrosis during lung fibrogenesis	45
miR‐199a‐3p	Caveolin‐2	Regulates proliferation and survival of endothelial and breast cancer cells	34
miR‐218	Caveolin‐2	Regulates migration and invasion in renal cell carcinoma	36
miR‐29a	Caveolin‐2	Inhibits endocytosis of pathogens during salmonella infection	43
miR‐22	Caveolin‐3	Regulates endothelial nitric oxide synthase activity during cardiac injury	44
miR‐150	–	Inhibits nuclear factor‐κB signalling by perturbing the recruitment of AKT/ARRB2/PDE4 into the lipid raft	46