Figure 2.
Longitudinal change in bone resorption outcomes by treatment arm. A, Model-based mean longitudinal changes in C-terminal telopeptide of collagen (CTx) by treatment arm and weeks on study. B, Model-based mean CTx percentage change from baseline by treatment arm and weeks on study. C, Model-based mean longitudinal changes in osteocalcin by treatment arm and weeks on study. D, Model-based mean osteocalcin percentage change from baseline by treatment arm and weeks on study. For each of the 4 panels, the vertical bars are the 95% confidence intervals and the numbers below the time points signify the number of subjects in each treatment group at each time interval. Abbreviations: ART, antiretroviral therapy; PL, active placebo; ZOL, zoledronic acid.