Table A2.
Variables Included in Statistical Analysis
| CSF Tumor-Derived cfDNA Cohort (n = 20), No. (%) | Absent Tumor-Derived CSF cfDNA Cohort (n = 21), No. (%) | P | |
|---|---|---|---|
| Age, mean (SD) | 55.0 (11.5) | 55.4 (11.6) | .92 |
| Sex | |||
| Male | 9 (45) | 8 (38) | .65 |
| Female | 11 (55) | 13 (62) | |
| Tumor histology | |||
| Breast | 6 (30) | 5 (24) | .42 |
| Lung | 7 (35) | 4 (19) | |
| Melanoma | 3 (15) | 3 (14) | |
| Others | 4 (20) | 9 (43) | |
| Anatomic location | |||
| Brain metastasis | |||
| Supratentorial | 7 (35) | 7 (33) | .06 |
| Infratentorial | 3 (15) | 0 (0) | |
| Supra- and infratentorial | 7 (35) | 4 (19) | |
| No brain metastasis | 3 (15) | 10 (48) | |
| Distant metastasis | |||
| Yes | 19 (95) | 16 (76) | .09 |
| No | 1 (5) | 5 (24) | |
| Prior CNS surgery | |||
| Yes | 8 (40) | 3 (14) | .06 |
| No | 12 (60) | 18 (86) | |
| Chemotherapy at the time of CSF collection | |||
| Yes | 17 (85) | 14 (67) | .17 |
| No | 3 (15) | 7 (33) | |
| Radiation therapy to CNS before CSF collection | |||
| Yes | 12 (60) | 9 (43) | .27 |
| No | 8 (40) | 12 (57) |