TABLE 1—

Biorepository Specimens: NHS and NHS II

Study	Year	Sample Type	Description	No. Samples
NHS
Main toenail cohort	1982–1984	Toenails	Nail clippings from all 10 toes	68 213
Main blood cohort	1989–1990	Blood		32 826
Main blood cohort, 2nd collection	2000–2002	Blood, urine	Only women who provided a 1st collection blood sample; first morning spot urine	18 743
Reproducibility study	1989–1990; 1991; 1992	Blood	Repeat blood samples from the same participants	227
Nested folate trial	1996; 1999	Blood	Repeat blood samples from the same participants	685
Main cheek cohort	2002–2004	Buccal cells	Among women without blood samples	33 040
Renal function cohort	2003;	Blood, urine	Repeat blood and urine samples from the same participants	1 992
	2007–2008
Cognitive function cohort	2007	Blood		130
Diet and lifestyle validation study	2009–	Blood, urine, saliva	4 24-h urine specimens; 2 blood specimens	375
NHS II
Main blood cohort	1996–1999	Blood	Among premenopausal women, samples were collected during the follicular and midluteal phases of the menstrual cycle	29 611
Reproducibility study	1996–1999; 2000; 2001	Blood, urine	Repeat blood and urine samples from the same participant	297
Renal function cohort	2003; 2008	Blood, urine	Repeat blood and urine samples from the same participants	1 847
Main cheek cohort	2004–2006	Buccal cells	Among women without blood samples	29 392
Melatonin study	2009	24-h urine		180
Diet and lifestyle validation study	2009–	Blood, urine, saliva	Four 24-h urine specimens; 2 blood specimens	375
Main blood cohort, 2nd collection	2008–2011	Blood, urine	Only women who provided a 1st collection blood sample; first morning spot urine	17 275
Diabetes and Women’s Health	2012	Blood, urine, toenails	Only women with a history of gestational diabetes mellitus	2 089
Mind Body Study	2013–2014	Blood, urine, timed saliva, stool, hair, toenails	Among the lifestyle validation study participants	250

Note. NHS = Nurses’ Health Study. Blood includes plasma, white blood cell count, and red blood cell count.