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. 2016 Jul;7(3):203–212. doi: 10.15412/J.BCN.03070305

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Copyright© 2016 Iranian Neuroscience Society

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Figure 5. — Comparison of Iba1 expression ratios among different age groups before SNL (preSNL), 5 days after SNL (postSNL) and after SNL plus administration of minocycline (30 mg/kg) (Unpaired t-test, n=6, *P<0.05, **P<0.01, and ***P<0.001). Iba1 ratio: Iba1/β-actin. The expression of Iba1 was significantly lower in juvenile rats than pup and mature ones (A). The ratio of Iba1 expression (post SNL/pre SNL) significantly increased after SNL; However, it was lower in juvenile rats than pup and mature rats (B). Moreover, after minocycline administration, the expression ratio was significantly lower in mature rats than pup and juvenile rats (C).