Figure 3. Neurons were generated from iPSCs from a sporadic AD patient or an age-matched control.

Immunostaining of neurons in culture with (A,D) Synapsin I (SYN-1) and (B,E) PSD-95, (C,F) overlay or (G,J) GFAP and (H,K) MAP2, (I,L) overlay. (M) Length of neurites from sporadic AD or control neurons presented as mean ± SEM of three independent experiments. ***Indicates significant difference (p ≤ 0.001), paired t-test.