Fig.2.

At 8 months into EMF treatment, cognitively-impaired AD mice (Tg) mice exhibited cognitive benefits and reduced brain Aβ deposition. A) Cognitive interference testing revealed Tg/EMF mice as vastly superior to Tg controls in 3-trial recall and retroactive interference performance. Even non-transgenic (NT) mice receiving EMF exposure showed better recall performance than NT controls, particularly early in recall testing. The final 2-day block of testing is shown from four days of testing. Upper graph: ^*p < 0.025 versus control; Lower graph: ^*p < 0.05 or higher level of significance versus control. B) Long-term EMF treatment significantly reduced total Aβ deposition in entorhinal cortex and hippocampus of Tg mice. Photomicrographic examples of typical Aβ immunostained-plaques from Tg and Tg/EMF mice are provided. ^*p < 0.02 versus Tg control group. Scale bar = 50 μm.