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Overexpression of TfR1 transgene leads to a significant down‐regulation of endogenous TfR1 mRNA and a dramatic increase in levels of TfR1 and ferritin protein. Relative quantification of (A) exogenous TfR1 transcripts, (B) endogenous TfR1 transcripts, (C) total TfR1 protein, (D) Fth1 transcripts and (E) Fth1 protein. (F) Representative western blot. Error bars represent SEM (n = 3).
