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(A) Event-free survival (EFS) and overall survival (OS) for eligible, evaluable enrolled participants. The 5-year EFS and OS rates were 75.3 ± 1.1% and 85.0 ± 0.9%, respectively. (B) EFS and OS for non–Down syndrome, non–very-high-risk randomly assigned participants. The 5-year EFS and OS rates were 77.5 ± 1.2% and 87.5 ± 0.9%, respectively.
