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. 2016 Aug 11;9:401. doi: 10.1186/s13104-016-2208-y

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Principal component analyses and UniFrac distances. a Unweighted principal component analyses showing β-diversity of fecal microbiota in mice pre- and post-vaccination with the indicated antigens, as detected via 16S rRNA amplicon sequencing. Principal component 1 (PC1) versus PC2 (left) and PC1 versus PC3 (right) are shown. Color-coding is identical to Fig. 2, with open symbols representing pre-vaccination and closed symbols representing post-vaccination samples. b Mean intragroup unweighted UniFrac distances between pre- and post-vaccination samples