Figure 3.

Interaction between change in FKBP5 methylation and FKBP5 genotype on primary anxiety response.

Note: Treatment response is depicted as reduction in primary anxiety disorder severity, which takes into account the baseline (pretreatment) severity, thus reflecting more accurately the models tested (which included pretreatment severity as a covariate). Note that a larger reduction in symptom severity represents a greater response to treatment. Interaction β = .20, 95% CI = .05–.35, P = .008.