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. 2015 Nov 9;26(4):533–541. doi: 10.1111/bpa.12331

Figure 3.

Figure 3

Reduced oxygenation of the precuneus in AD was associated with elevated EDN1. A. Bar chart showing significantly increased EDN1 in AD within the precuneus. B. Bar chart showing increased EDN1 levels in relation to disease severity when control and AD cases were subdivided according to Braak tangle stage (0–II, III–IV and V–VI) irrespective of the presence or absence of a history of dementia. Scatterplots showing the inverse correlation between EDN1 concentration and MAG:PLP1 ratio (r = −0.31) (C) and the positive correlation between EDN1 and VEGF (r = 0.29) (D). *P < 0.05, ***P < 0.001, ****P < 0.0001.