Table 1.

Changes in miRNA Expression in Late Gastrula Stage 13 lin28 Morphant Embryos^a

miRNA	Mean control	Mean AMO	Fold change in morphant relative to control	Member of mir‐106∼363 cluster	Member of mir‐17∼92 cluster
xtr‐miR‐20a	1.50	0.51	−2.9		X
xtr‐miR‐17‐5p	1.26	0.52	−2.4		X
xtr‐miR‐200a	1.25	0.59	−2.1
xtr‐miR‐20b	1.29	0.61	−2.1	X
xtr‐miR‐301	1.14	0.54	−2.1
xtr‐miR‐363‐3p	1.28	0.60	−2.1	X
xtr‐miR‐19a	1.36	0.67	−2.0		X
xtr‐miR‐19b	1.27	0.63	−2.0	X
xtr‐miR‐428	1.27	0.63	−2.0
xtr‐miR‐200b	1.37	0.71	−1.9
xtr‐miR‐130b	1.32	0.86	−1.5
xtr‐miR‐203	1.14	0.75	−1.5
xtr‐miR‐30b	1.13	0.90	−1.3
xtr‐miR‐125a	1.27	1.11	−1.1
xtr‐miR‐126	2.46	2.43	−1.0
xtr‐miR‐427	1.09	1.04	−1.0
xtr‐let‐7c	1.10	1.20	−0.9
xtr‐let‐7a	1.16	1.14	1.0
xtr‐let‐7e	0.97	0.99	1.0
xtr‐miR‐155	1.09	1.15	1.1
xtr‐miR‐22	0.92	1.00	1.1
xtr‐miR‐7	0.93	1.27	1.4

^aThe expression of Xenopus miRNAs in lin28 morphants and control embryos at late gastrula stage 13. Expression levels are shown as ratios relative to abundance in a mixed stage reference RNA sample. Only miRNAs flagged as being detected in all three replicate arrays are included. miRNAs showing ≥ 2 fold change and P ≤ 0.05 are shown in italic type. Memberships of mir‐106∼363 and mir‐17∼92 clusters are indicated.