Table 3.
External validation of the models for the probability of a thromboembolic event.
| Performance measure | Calibration slope (s.e.) | C‐statistic (s.e.) | Brier score |
|---|---|---|---|
| MLE | 0.78 (0.12) | 0.704 (0.025) | 0.03396 |
| BE | 0.85 (0.13) | 0.703 (0.025) | 0.03381 |
| RIDGE | 1.27 (0.18) | 0.724 (0.024) | 0.03357 |
| LASSO | 1.23 (0.17) | 0.718 (0.024) | 0.03359 |
| ENET | 1.22 (0.17) | 0.723 (0.024) | 0.03358 |
| ALASSO | 1.07 (0.16) | 0.715 (0.026) | 0.03361 |
| SCAD | 1.07 (0.16) | 0.697 (0.026) | 0.03370 |
| BLASSO | 1.26 (0.17) | 0.723 (0.024) | 0.03360 |
| SSVS | 1.19 (0.17) | 0.718 (0.024) | 0.03359 |
Performance measures were evaluated on a validation data set with 2739 patients and 97 events. MLE, maximum likelihood estimation; BE, backwards elimination; LSF, linear shrinkage factor; ENET, elastic net; ALASSO, adaptive lasso; BLASSO, Bayesian lasso; SSVS, stochastic search variable selection; SCAD, smoothly clipped absolute deviation.