Table 2. Diagnostic performance of RDT and microscopy for Plasmodium infections in children in 3 districts, southwestern Uganda*.
Diagnostic accuracy of RDT† | Plasmodium infection | P. falciparum infection | Non–P. falciparum infection‡ |
---|---|---|---|
Sensitivity (95% CI) | 63.6 (40.7–82.8) | 75.0 (42.8–94.5) | 10.0 (0.3–44.5) |
Specificity (95% CI) | 95.4 (93.4–96.9) | 95.1 (93.1–96.7) | 99.8 (99.1–100.0) |
PPV (95% CI) | 33.3 (19.6–49.5) | 23.1 (11.1–39.3) | 50.0 (1.3–98.7) |
NPV (95% CI) | 98.6 (97.3–99.4) | 99.5 (98.5–99.9) | 98.6 (97.3–99.3) |
Agreement, % | 94.3 | 94.8 | 98.3 |
κ |
0.41 |
0.33 |
0.15 |
*NPV, negative predictive value; PPV, positive predictive value; RDT, rapid diagnostic test. †SD Bioline Malaria Ag Pf/Pan (P. falciparum or other Plasmodium species; Standard Diagnostics, Gyeonggi-do, South Korea). ‡Children with mixed infections were excluded from analysis. |