Table 2.
Guideline | Last updated | Age categories (years) | Preferred step up choices after initial low dose ICS | Specifies indications for starting low dose ICS | Specifies indications for starting moderate dose ICS | Specifies indications for starting high dose ICS | Describes adverse effects | Review interval for dose drop |
---|---|---|---|---|---|---|---|---|
GINA | 2016 | Up to 5 | Mod dose ICS or add LTRA | Yes | Yes | Yes | Yes | 3 months |
6–11 | Mod dose ICS | |||||||
12 and older | Add LABA | |||||||
Australia | 2015 | 0–1 | NS | Yes | NS | NS | NS | NS |
1–2 | NS | |||||||
2–5 | NS | |||||||
6 and older | NS | |||||||
Canada Preschool | 2015 | 1–5 | Mod dose ICS | Yes | Yes | NS | NS | 3 months |
Canada Older | 2012 | 6–11 | Mod dose ICS | Yes | NS | NS | Yes (CTS 2010) | weeks to months |
12 and older | Add LABA | |||||||
SIGN | 2014 | 0–4 | LTRA | Yes | NS | NS | Yes | 3 months |
5–12 | Add LABA | |||||||
13 and older | Add LABA | |||||||
ICON | 2012 | Describes other guidelines | Describes other guidelines | NS | NS | NS | NS | NS |
Saudi Arabia (SINA) | 2012 | <5 | Mod dose ICS | Yes | NS | NS | Yes | 3–6 months |
5 and older | Add LABA | |||||||
Japan | 2012 | <2 | LTRA is first choice, not ICS. Step-up: mod dose ICS | Yes | Yes | Yes | NS | 3 months |
2–5 | Mod dose ICS | |||||||
6–15 | LABA or mod dose ICS | |||||||
South Africa | 2009 | <5 | Mod dose ICS | Yes | NS | NS | Yes | 3 months |
5 and older | LTRA or LABA or mod dose ICS | |||||||
PRACTALL | 2008 | 0–2 | NS | NS | NS | Yes | NS | |
3–5 | Mod dose ICS or add LTRA | |||||||
6 and older | Mod dose ICS or add LTRA | |||||||
NHLBI | 2007 | 0–4 | Mod dose ICS | Yes | NS | NS | Yes | 3 months |
5–11 | Mod dose ICS or add LABA | |||||||
12 and older | Add LABA | |||||||
India | 2003 | <5 | Mod dose ICS | Yes | NS | NS | Yes | 3–6 months |
5 and older | Add LABA |