FIGURE 2.

Schematic representation of the circularized KSHV genome. The terminal repeats (TRs), in blue, comprise around 20% of the genome. KSHV open reading frames (ORF) are in brown, miRNAs are in dark gray and non-coding long RNA PAN is in light gray. Alternative protein names are written in parenthesis. Arrows indicate transcription direction. Although KSHV persistence is the focus of this article, most KSHV genes are shown. This map was generated from the HHV-8 complete genome sequence (Genbank accession AF148805) strain GK18 using SerialCloner software.