TABLE 1.
Case | Age, y |
Sex | Location | Imaging Modality |
Size on Imaging, cm |
Additional Radiologic Findings |
Radiologic Diagnosis |
Cytologic Diagnosis |
Histologic Diagnosis | Size of Invasion, cm |
Follow-Up |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 57 | Man | Head | MRI | 6.6 | Mass communicates with pancreatic duct (7.5 mm) |
Cystic and solid mass PDAC |
PDAC with intraductal component |
IOPN, 6.5 cm; negative margins |
None identified | ANED at 38 mo |
2 | 56 | Woman | Head | CT | 5.6 | Cystic mass in main and branch PDs with papillary projections and dilatation of PD to 3.3 cm |
MD-IPMN with invasive component |
IPMN vs cystic PDAC |
IOPN, 8.7 cm, with minute focus of PDAC; margin positive for IPMN, LNs negative, confined to pancreas |
0.3 with focal extravasated mucin |
ANED at 15 mo |
3 | 68 | Woman | Head | CT | 4.3 | Cystic mass in pancreatic head with pancreatic duct dilatation to 7 mm |
Cystic mass | IOPN, with high-grade atypia |
IPMN, 3.3 cm, with high-grade dysplasia/carcinoma in situ; negative margins and LNs |
None | LTF/U |
4 | 84 | Man | Head | MRI | 2.5 | Dilated CBD 7 mm and pancreatic duct 6 mm; thickened septae and thick fluid observed |
Mucinous cyst: MCN vs IPMN |
IOPN | IOPN, 2.2 cm, minute focus suspicious for PDAC; negative margins, LNs |
0.1 | Perioperative death, 23 d postsurgery |
5 | 64 | Woman | Body | MRI | 3.7 | Solid, circumscribed mass with central cystic component; PD dilated to 6 mm |
PDAC | IOPN, with high-grade atypia, suspicious for invasion |
IOPN, 4.5 cm, multifocal PDAC; negative margins, 5 of 17 LNs positive |
<2 cm aggregate microscopic measurement |
ANED at 9 mo, receiving chemotherapy |
Abbreviations: ANED, alive with no evidence of disease; CBD, common bile duct; CT, computerized tomography scan; IOPN, intraductal oncocytic papillary neoplasm; LNs, lymph nodes; LTF/U, lost to follow-up; MCN, mucinous cystic neoplasm; MD-IPMN, main duct-intraductal papillary mucinous neoplasm; MRI, magnetic resonance imaging; PD, pancreatic duct; PDAC, pancreatic ductal adenocarcinoma.