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A diagram of CYP2D6, CYP3A5 polymorphisms, and breast cancer outcomes from previous research.
Abbreviations: TAM, tamoxifen; NDMT, N-desmethyl-tamoxifen; 4OHT, 4-hydroxy-tamoxifen; END, endoxifen; OS, overall survival; PFS, progress-free survival; CB, clinical benefit; IDFS, invasive disease-free survival; DFS, disease-free survival.
