Table 2.

Phenotype classification by the conventional method

Genotype	Phenotype	Genotype	Phenotype
Functional/functional	EM	Reduced/reduced	IM
Functional/reduced	EM	Reduced/null	IM
Functional/null	EM	Null/null	PM

Notes: Functional alleles = CYP2D6*1, CYP2D6*2, and CYP3A5*1. Reduced allele = CYP2D6*10. Null alleles = CYP2D6*4 and CYP3A5*3.

Abbreviations: EM, extensive metabolizer; IM, intermediate metabolizer; PM, poor metabolizer.