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. 2016 Aug 11;9:51–65. doi: 10.4137/IJTR.S38190

Figure 1.

Figure 1

The hepatic kynurenine pathway of tryptophan degradation up to the kynureninase step. Abbreviations are in parentheses. Benserazide (BSZ) and carbidopa (CBD) are shown as kynureninase inhibitors. Adapted from Ref. 1. Badawy AA-B, Bano S. Elevation of kynurenine metabolites in rat liver and serum: a potential additional mechanism of the alcohol aversive and anti-cancer effects of disulfiram? Alcohol Alcohol. 2016;51:20–5.1