Table 5.

Effects of chronic administration of tryptophan and benserazide separately or in combination on liver kynureninase and KAT activities.

TREATMENT GROUP	KYNURENINASE	KYNURENINE AMINOTRANSFERASE
Control	7.46 ± 0.28	1.12 ± 0.03
Benserazide	*6.12 ± 0.42	*0.44 ± 0.02
Tryptophan	7.40 ± 0.39	0.97 ± 0.09
Benserazide + tryptophan	*5.56 ± 0.73*	*0.32 ± 0.01*¶

Notes: Treatment details are as in Table 3. Values are mean ± SEM for five rats per group. Enzyme activities are expressed in nmol of product formed/min per mg of protein. The asterisk on the left denotes a significant difference from controls. Symbols on the right denote significant differences between the BSZ + Trp group and the Trp (^*) or BSZ (^¶) group. Symbols denote significance levels (P) of 0.037–0.001.