Table 3.
Cohort 2: Comparison of the genotypes of rs4918 (mean ±SD).
| Parameter | CC homozygotes (n=81) | CG heterozygotes (n=61) | GG homozygotes (n=15) | p* |
|---|---|---|---|---|
| AHSG (mg/l) | 682±125 | 680±94 | 611±102 | 0.185 |
| BMI (kg/m2) | 28.6±3.8 | 27.2±4.5 | 27.5±5.0 | 0.048 0.204** |
| Abdominal circumference (cm) | 103±10 | 101±12 | 100±11 | 0.333 |
| Waist circumference (cm) | 106±8 | 102±9 | 102±9 |
0.005 0.026** |
| Total cholesterol (mmol/l) | 5.38±1.26 | 5.10±1.13 | 5.43±1.25 | 0.673 |
| LDL-cholesterol (mmol/l) | 3.23±0.97 | 3.11±0.96 | 3.32±0.76 | 0.618 |
| HDL-cholesterol (mmol/l) | 1.23±0.28 | 1.20±0.27 | 1.10±0.27 | 0.112 |
| Triglyceride (mmol/l) | 1.90±1.17 | 1.76±0.80 | 1.66±0.58 | 0.934 |
| TNFα (pg/ml) | 6.07±1.70 | 6.15±1.88 | 5.89±1.75 | 0.848 |
| Adiponectin (μg/ml) | 9.29±4.13 | 8.63±4.30 | 8.53±3.21 | 0.486 |
| Resistin (ng/ml) | 9.24±5.73 | 10.19±7.11 | 8.93±4.03 | 0.756 |
| Leptin (ng/ml) | 32.2±19.3 | 29.2±18.0 | 31.0±10.6 | 0.676 |
| C-peptide (ng/ml) | 3.36±2.26 | 3.05±1.79 | 3.87±3.35 | 0.866 |
| Glucose (mmol/l) | 5.51±1.68 | 5.93±1.74 | 5.43±0.75 | 0.275 |
| Insulin (μU/ml) | 24.2±16.0 | 22.1±12.9 | 27.6±22.6 | 0.850 |
*
Kruskal-Wallis test in all parameters;
**
CC vs. GG, when post hoc p<0.05