Table 5.
Cohort 2: Association between BMI and rs4918 polymorphism. A: genotypes (CC, CG, GG), B: distribution of the G allele.
| A | Genotype | BMI (kg/m2) | Total | |||
|---|---|---|---|---|---|---|
| 0–25 | 26–29 | 30–39 | 40 or more | |||
| Patients without diabetes | CC | 13 | 22 | 22 | 0 | 57 |
| CG | 16 | 20 | 4 | 0 | 40 | |
| GG | 5 | 4 | 2 | 1 | 12 | |
| Total | 34 | 46 | 28 | 1 | 109 | |
|
Chi square: 19.671, p=0.003 Linear-by-linear association value: 4.416, p=0.036 | ||||||
| Patients with diabetes | CC | 7 | 8 | 9 | 0 | 24 |
| CG | 6 | 5 | 9 | 1 | 21 | |
| GG | 1 | 2 | 0 | 0 | 3 | |
| Total | 14 | 15 | 18 | 1 | 48 | |
|
Chi square: 4.201, p=0.649 Linear-by-linear association value: 0.011, p=0.918 | ||||||
| All patients in cohort 2 | CC | 20 | 30 | 31 | 0 | 81 |
| CG | 22 | 25 | 13 | 1 | 61 | |
| GG | 6 | 6 | 2 | 1 | 15 | |
| Total | 48 | 61 | 46 | 2 | 157 | |
|
Chi square: 11.479, p=0.075 Linear-by-linear association value: 3.314, p=0.075 | ||||||
| B | Allele | BMI (kg/m2) | Total | |||
| 0–25 | 26–29 | 30–39 | 40 or more | |||
| Patients without diabetes | G | 21 | 24 | 26 | 1 | 52 |
| Non-G | 13 | 22 | 22 | 0 | 57 | |
| Total | 34 | 46 | 28 | 1 | 109 | |
|
Chi square: 11.908, p=0.008 Linear-by-linear association value: 7.420, p=0.006 | ||||||
| Patients with diabetes | G | 7 | 7 | 9 | 1 | 24 |
| Non-G | 7 | 8 | 9 | 0 | 24 | |
| Total | 14 | 15 | 18 | 1 | 48 | |
|
Chi square: 1.067, p=0.785 Linear-by-linear association value: 0.111, p=0.739 | ||||||
| All patients in cohort 2 | G | 28 | 31 | 15 | 2 | 76 |
| Non-G | 20 | 30 | 31 | 0 | 81 | |
| Total | 48 | 61 | 46 | 2 | 157 | |
|
Chi square: 11.479, p=0.075 Linear-by-linear association value: 3.314 p=0.075 | ||||||
Mantel-Haenszel statistics