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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Medchemcomm. 2016 Jun 20;7(8):1672–1680. doi: 10.1039/C6MD00277C

Table 1.

IC50 (µM) of 1a–g for a selected panel of PTPs.

1a 1b 1c 1d 1e 1f 1g
mPTPB - 179.5
± 19		 351.0
± 154		 - 148.4
± 6		 105.6
± 10		 -
SHP2 - 201.8
± 37		 392.2
± 71		 - 136.0
± 28		 114.8
± 17		 -
PTP1B - 360.2
± 207		 - - 422.4
± 311		 260.4
± 47		 -
CD45 - 207.1
± 17		 - - 157.2
± 14		 112.4
± 9		 -
LYP - 302.9
± 165		 - - 268.4
± 149		 133.9
± 34		 -
FAP-1 - 454.3
± 754		 - - 448.8
± 1506		 127.9
± 85		 -

A “-“ indicates IC50 >> 500 µM.