Table 1.

Treatment schedule for in vivo experiments in which TAT‐ODD‐procaspase‐3 (TOP3) was combined with gemcitabine (Gem) or TS‐1 in a SUIT‐2 orthotopic pancreatic cancer model

Group	n	Drug	Dose, mg/kg	Schedule
Control	9	–	–	–
TOP3	8	TOP3	10	Every 3 days, i.p.
Gem	8	Gem	50	Every 3 days, i.p.
TOP3+Gem	8	TOP3	10	Every 3 days, start at day +1
		Gem	50	Every 3 days, start at day 0
Control	8	–	–	–
TOP3	7	TOP3	10	Every 4 days, i.p.
TS‐1	8	TS‐1	10	5 consecutive days/week, p.o.
TOP3+TS‐1	8	TOP3	10	Every 4 days, i.p.
		TS‐1	10	5 consecutive days/week, p.o.

n, number of treated mice; i.p., intraperitoneal injection; p.o., oral administration.