Table 3.
Multivariate analysis of overall survival in patients with grade II–III glioma
| Variable | Hazard ratio (95% CI) | P‐value |
|---|---|---|
| Age | 1.022 (1.001–1.044) | 0.043 |
| Gender | 1.090 (0.585–2.034) | 0.786 |
| KPS | 0.948 (0.911–0.986) | 0.008 |
| WHO grade II versus III | 0.628 (0.414–0.955) | 0.030 |
| MIB‐1 | 0.989 (0.967–1.012) | 0.357 |
| Tumor type (astrocytic vs oligodendroglial) | 1.581 (1.039–2.405) | 0.033 |
| Surgery (TR + STR) versus (PR + biopsy) | 0.259 (0.123–0.547) | 0.001 |
| Radiotherapy versus none | 0.438 (0.289–0.848) | 0.012 |
| Chemotherapy versus none | 1.757 (0.701–4.402) | 0.229 |
| IDH1/2 mutant versus wild type | 0.218 (0.100–0.474) | <0.001 |
CI, confidence interval; KPS,; MIB‐1, positive rate (%); PR, partial resection; STR, subtotal resection; TR, total resection.