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Histological analysis (H&E staining) of sagittal sections of maxillary incisors at E15 (A-D). The arrows indicate rudimentary tooth germs in the maxillary incisors of Usag-1+/+/Runx2+/+(A), Usag-1-/-/Runx2+/+ (C), and Usag-1-/-/Runx2-/- (D) mice. The arrowhead indicates a lingual bud that formed in the incisor of a Usag-1+/+/Runx2-/- mouse (B).
