Table 1. The phenotypes of Usag-1^+/+/Runx2^+/+, Usag-1^+/+/Runx2^-/-, Usag-1^-/-/Runx2^+/+ and Usag-1^-/-/Runx2^-/- mice at E15 and P0.

E15	Usag-1+/+/Runx2+/+	Usag-1+/+/Runx2-/-	Usag-1-/-/Runx2+/+	Usag-1-/-/Runx2-/-
number	5	6	6	6
Developmental stage of tooth germ (incisors)	Late cap stage	Cap stage	Late cap stage	Late cap stage 50%
				Cap stage 50%
Developmental stage of tooth germ (molars)	Late cap stage	Bud stage	Late cap stage	Late cap stage 50%
Formation of lingual buds	incisors 0%	incisors 100%	incisors 0%	incisors 50%
	molars 0%	molars 100%	molars 0%	molars 67%
Incidence rate of rudimentary incisor tooth germs	Maxilla 80%	Maxilla 0%	Maxilla 100%	Maxilla 83%
	Mandible 20%	Mandible 0%	Mandible 83%	Mandible 16%
P0	Usag-1+/+/Runx2+/+	Usag-1+/+/Runx2-/-	Usag-1-/-/Runx2+/+	Usag-1-/-/Runx2-/-
number	3	3	6	4
Tooth morphology (incisors)	Normal	Abnormal	Normal	Normal 25%
				Abnormal 75%
Tooth morphology (molars)	Normal	Developmental arrest	Normal	Normal 25%
				Bell stage 75%
Incidence rate of supernumerary teeth (incisor)	Maxilla 0%	Maxilla 0%	Maxilla 100%	Maxilla 25%
	Mandible 0%	Mandible 0%	Mandible 100%	Mandible 0%