TABLE 1.

Effect of lysosomal or proteasomal inhibitors on cell viability

Drug	n	Viability (vehicle) (%)	Viability (drug) (%)
MG132	5	90 ± 3	64 ± 9 (P = 0.0227)
Proteasome inhibitor I	3	88 ± 3	69 ± 6 (P = 0.0457)
Lactacystin A	3	97 ± 3	81 ± 1 (P = 0.036)
Bafilomycin A	3	96 ± 3	92 ± 4 (ns)

Basophils were cultured in medium + 10 ng/ml IL-3 for 24 h, with or without the drugs shown. MG-132 was at 5 µM, proteasome inhibitor I at 5 µM, lactacystin A at 40 µM, and bafilomycin A at 200 nM. Viability was determined with erythrosin B staining.