Table 4.

Comparison of hazard ratios for NHBs vs. NHWs and assessment of model fit across all sequential competing risk modeling analyses for the primary outcome of graft loss

Model	Domain	Fixed Entry				Varied Entry*
		HR for NHB vs. NHW	95% CI	p-Value	Model AIC	Relative change in NHB HRs vs. NHW as compared to previous model	Change in AICs from previous model
Model 1	Race Only	1.999	1.61–2.49	<0.0001	4868	NA	NA
Model 2	+Sociodemographics	2.054	1.64–2.57	<0.0001	4875	−2.8 to 2.1%	5 to 7
Model 3	+Comorbidities	2.057	1.65–2.57	<0.0001	4877	0.1 to 1.3%	2 to 4
Model 4	+Donor Characteristics	1.781	1.36–2.32	<0.0001	4870	−13.4 to −4.2%	−7 to 3
Model 5	+Immunologic Risks	1.697	1.30–2.22	0.0001	4878	−9.6 to −4.7%	6 to 8
Model 6	+Immunosuppression	1.691	1.29–2.22	0.0001	4885	−0.4 to 0.7%	7 to 9
Model 7	+CVD Risk Factors & Control	1.501	1.12–2.01	0.0059	4773	−17.5 to −8.7%	−118 to −106
Model 8	+Post-Transplant Events	1.490	1.11–1.99	0.0072	4757	−5.5 to −0.7%	−28 to −16

^*Varied entry was conducted using iterative modeling and changing the introduction of the blocks of variables into the model in order to determine their impact on racial disparities. For all scenarios, race was initially entered into the model (unadjusted risk), followed by entry of blocks of variables which varied across different iterations.