Fig. 3.

Inhibition of miR-181c affects outgrowth in cortical neurons. a Representative images of DIV9 neurons infected with control or sponge-miR-181c lentiviruses. b Quantification of total dendritic length. c Graph showing the number of branching points of control and sponge-miR-181c infected neurons. d Quantification of the number of branches per branch order. Data are shown as mean ± SEM; p values are determined by two-tailed unpaired Student’s t test. *p ≤ 0.05; **p ≤ 0.01. e Sholl analysis revealing dendritic arborisation of neurons infected with either control (black line) or sponge-miR-181c (gray line) lentivirus. Data are shown as mean ± SEM; p values are determined by two-way ANOVA followed by Bonferroni multiple comparisons test. *p ≤ 0.05