Table 1.

Clinical implications of genetic variation at the 4q25 locus for AF

Condition	SNPs	Study size	OR	CI	P value	References
Cardioversion success	rs2200733 rs10033464	184	2.1	1.2–3.3	8×10−3	44
AF recurrence post ablation	rs220073 rs10033464	200	0.76	0.6–1.0	0.016	42
	rs2200733 rs10033464	195	2.0	1.0–3.8	0.039	47
Antiarrhythmic drug response	rs10033464	399	4.7	1.8–12	1.3×10−3	43
Stroke	rs2200733	6,222	1.3	1.2–1.4	2.18 × 10−12	51
	rs1906591	4,199	1.6	1.4–1.9	9.2×10−12	57
Sudden cardiac death	rs2200733	27,629	1.3	1.1–1.5	7.9×10−4	58