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(A) Dilation of parenchymal arterioles to NS-309. (B) Effect of SLX-2119 or vehicle (DMSO) on myogenic tone in brain parenchymal arterioles. (C) Responses of pial arterioles in vivo to SLX-2119 in the absence and presence of L-NNA (100 μmol/L). (A) n=8 parenchymal arterioles. (B) n=5 parenchymal arterioles for both groups, *P<0.001 for SLX-2119 vs. vehicle. (C) n=3, *P<0.05 for SLX-2119 + L-NNA vs. SLX-2119 alone.
