Figure 1. Effect of various modeling assumptions on QALYs gained in comparison with the base model (56 QALYs gained).
The assumptions are: 1) no overdiagnosis, 2) screen attendance of 50% and 100%, 3) all unfavorable and favorable utility estimates, 4) utility estimate of 0.93 and 1 for the life-time post-recovery period, 5) utility estimate of 0.86 and 0.24 for palliative therapy, and 6) the utility estimates for the post-recovery period (0.95) and palliative therapy (0.6) as used in the base model combined with the unfavorable and favorable utility estimates of all other health states.