Table 1.
Clinicopathological characteristics
No LLND (n = 145) | Unilateral LLND (n = 73) | Bilateral LLND (n = 133) | p* | p** | |
---|---|---|---|---|---|
Sex ratio (M:F) | 96:49 (66:34) | 47:26 (64:36) | 86:47 (65:35) | 0.95 | 0.97 |
Mean age (years) | 61 | 57 | 57 | 0.03 | 0.98 |
Operation | |||||
Sphincter-saving | 112 (77) | 36 (49) | 63 (47) | ||
Not sphincter-saving | 33 (23) | 37 (51) | 70 (53) | <0.001 | 0.79 |
Adjuvant chemotherapy | |||||
No | 139 (96) | 67 (92) | 121 (91) | ||
Yes | 6 (4) | 6 (8) | 12 (9) | 0.24 | 0.85 |
T-stage | |||||
T1 | 52 (36) | 3 (4) | 3 (2) | ||
T2 | 47 (32) | 27 (37) | 37 (28) | ||
T3 | 46 (32) | 40 (55) | 83 (62) | ||
T4 | 0 (0) | 3 (4) | 10 (8) | <0.001 | 0.37 |
Meso LN positive | |||||
0 | 102 (70) | 44 (60) | 64 (48) | ||
1–3 | 30 (21) | 19 (26) | 39 (29) | ||
>4 | 13 (9) | 10 (14) | 30 (23) | 0.003 | 0.28 |
Lat LN positive | |||||
No | – | 62 (85) | 109 (82) | ||
Yes | – | 11 (15) | 24 (18) | – | 0.59 |
ANP | |||||
No | 3 (2) | 2 (3) | 17 (13) | ||
Yes | 142 (98) | 71 (97) | 116 (87) | <0.001 | 0.02 |
Differentiation | |||||
Well | 75 (52) | 27 (37) | 50 (38) | ||
Moderate | 67 (46) | 44 (60) | 75 (56) | ||
Poor | 2 (2) | 2 (3) | 8 (6) | 0.18 | 0.29 |
Tumor size | |||||
0–4 cm | 106 (73) | 31 (42) | 42 (32) | ||
>4 cm | 39 (27) | 42 (58) | 91 (68) | <0.001 | 0.12 |
Diss. LN (mean) | 21 | 38 | 45 | <0.001 | 0.004 |
Values in parentheses are percentages
* p value between no LLND, unilateral LLND, and bilateral LLND
** p value between unilateral LLND and bilateral LLND
Meso mesorectal; Lat lateral; LN lymph node; ANP autonomic nerve preservation